Etiology of the liver granulomatous response in Schistosoma mansoni-infected athymic nude mice
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چکیده
منابع مشابه
Passive avoidance response in mice infected with Schistosoma mansoni.
Schistosomiasis is a parasitic disease of humans and rodents affecting more than 200 million people worldwide. Following the onset of infection, the worms induce granulomas around schistosome eggs in the liver, intestine and central nervous system (both brain and spinal cord), which are likely to cause changes in cognitive functions. In the present study, CD-1 female mice were percutaneously in...
متن کاملBrain schistosomiasis in mice experimentally infected with Schistosoma mansoni.
Introduction Human neuroschistosomiasis has been reported in the literature, but the possibility of modeling neuroschistosomiasis in mice is controversial. Methods In two research laboratories in Brazil that maintain the Schistosoma mansoni life cycle in rodents, two mice developed signs of brain disease (hemiplegia and spinning), and both were autopsied. Results S. mansoni eggs, both with and ...
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M e t h o d s genera l ly u t i l ized for s t u d i e s o n a n a p h y l a x i s t o p r o t e i n a n t i g e n s s u c h a s d e t e r m i n a t i o n of h i s t a m i n e re l ease t o t h e b lood , h e m o c o n c e n t r a t i o n , h i s t a m i n e r e l ea se f r o m p e r i t o n e a l m a s t cells a n d pas s ive c u t a n e o u s a n a p h y l a x i s (PCA) w e r e u s e d t o i ...
متن کاملAntischistosomal and liver protective effects of Curcuma longa extract in Schistosoma mansoni infected mice.
With a view to clarify the induction of the "Crabtree consequence" in liver cells of S. mansoni infected mice, the curative effect of oil extract of C. longa was tested and compared to praziquantel (PZQ) the effective drug against all schistosome species occurring in man. Protein, glucose, glucose-6-phopsphatase, AMP-deaminase, adensoine deaminase, urea concentration, pyravate kinase (PK), phos...
متن کاملTherapy with bone marrow cells reduces liver alterations in mice chronically infected by Schistosoma mansoni.
AIM To investigate the potential of bone marrow mononuclear cells (BM-MCs) in the regeneration of hepatic lesions induced by Schistosoma mansoni (S.mansoni) chronic infection. METHODS Female mice chronically infected with S.mansoni were treated with BM-MCs obtained from male green fluorescent protein (GFP) transgenic mice by intravenous or intralobular injections. Control mice received inject...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1980
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.27.1.75-80.1980